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Anjon Audhya leads research on essential proteins
Audhya is heading the research team that aims to gain a deeper understanding of the functioning of the COPII.
Under the leadership of Anjon Audhya, scientists are exploring the mechanisms by which a set of proteins carries out its vital functions. / Image - University of Wisconsin–Madison
Scientists at the University of Wisconsin–Madison, under the leadership of Anjon Audhya, are leveraging state-of-the-art cell imaging and genome editing technology to explore the mechanisms by which a set of proteins carries out its vital functions.
The breakthrough has the potential to enhance researchers' understanding of various diseases, including cancer, diabetes, and those affecting immune function. Moreover, it may contribute to the development of new treatments for these conditions.
Audhya, who serves as a professor in the Department of Biomolecular Chemistry, is heading the research team that aims to gain a deeper understanding of the functioning of the Coat Protein Complex II or COPII.
The research team recently published a paper in Nature Communications, explaining their findings in which Audhya likened the results to the postal system analogy. While scientists understood that COPII operates similarly to postal workers in picking up and delivering parcels, the study marked the first instance of tracking these "workers" as they sorted packages through the cell's distribution and delivery systems.
“We can now see that envelope in the mailbox, see how the mail carrier comes to the mailbox to pick up the letter and then drive away,” said Audhya, who also serves as senior associate dean for basic research, biotechnology, and graduate studies at the School of Medicine and Public Health.
Audhya leads an internationally recognized research program that concentrates on unraveling the fundamental mechanisms governing the transportation of membrane proteins, lipids, and other macromolecules throughout eukaryotic cells.
In his role as the leader of the school's Office of Basic Research, Biotechnology, and Graduate Studies, Audhya oversees various programs and initiatives. These efforts are dedicated to mentoring and supporting faculty and students in securing research funding, applying for grants, managing grant funds, and navigating technology transfer processes.
Audhya obtained his bachelor's degree from Brown University and PhD in biomedical sciences at the University of California, San Diego. Following his doctoral studies, he completed a postdoctoral fellowship at the Ludwig Institute for Cancer Research in La Jolla.
He has received several prestigious accolades, including the Shaw Scientist Award, an American Cancer Society Research Scholar Award, the H. I. Romnes Faculty Fellowship, and recognition as a RIDE Scholar.
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